Cholesterol-enriched diet disrupts the blood-testis barrier in rabbits

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Cholesterol-enriched diet disrupts the blood-testis barrier in rabbits

Morgan DH, Ghribi O, Hui L, Geiger JD, Chen X. Cholesterolenriched diet disrupts the blood-testis barrier in rabbits. Am J Physiol Endocrinol Metab 307: E1125–E1130, 2014. First published October 21, 2014; doi:10.1152/ajpendo.00416.2014.—About 15% of heterosexual couples in the USA suffer from infertility issues; male infertility accounts for 50% of all infertility cases and roughly 50% of male...

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Re: Cholesterol-Enriched Diet Disrupts the Blood-Testis Barrier in Rabbits.

About 15% of heterosexual couples in the USA suffer from infertility issues; male infertility accounts for ∼50% of all infertility cases and roughly 50% of male infertility is idiopathic. Increased levels of plasma cholesterol affect spermatogenesis and male fertility negatively, but by unclear mechanisms. Clearly, spermatogenesis occurs in immune-privileged seminiferous tubules that are protec...

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Hypocholesterolemic effects of Balangu (Lallemantia royleana) seeds in the rabbits fed on a cholesterol-containing diet

Objectives: Lallemantia royleana (Benth. in Wall.) Benth. (Lamiaceae) is a medicinal plant used in Iranian traditional and folklore medicine in the treatment of various nervous, hepatic, and renal diseases. In the present study, whole seeds of the herb were prepared and evaluated for hypolipidemic activities using an animal model. Materials and Methods: Animals were fed normal diets or diets su...

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Drugs and the blood-testis barrier

The functional and morphological evidence for the blood-testis barrier is discussed, together with evidence for the various processes (simple diffusion and facilitated diffusion) by which various substances enter the seminiferous tubule. Data are presented to show that methylmethane-sulfonate (MMS) and dimethylnitrosamine (DMNA) both enter the seminiferous tubules rapidly, although from the pub...

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effect of ascorbic acid on blood serum lipids in male rabbits fed high-cholesterol diet

introduction atherosclerosis is a disease which begins during childhood. oxidation of lipoproteins is an important factor implicated in atherosclerosis. vitamin c decreases blood serum lipids and may inhibit atherosclerosis. this study was designed to observe the effect of ascorbic acid on blood serum lipids in male rabbits fed high-cholesterol diet. methods twenty white male rabbits were weigh...

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ژورنال

عنوان ژورنال: American Journal of Physiology-Endocrinology and Metabolism

سال: 2014

ISSN: 0193-1849,1522-1555

DOI: 10.1152/ajpendo.00416.2014